Reproductive Health Matters
Volume 12, Issue 24, Supplement , Pages 57-64 , November 2004

Misoprostol Alone for Early Medical Abortion in a Latin American Clinic Setting

  • Deborah L Billings

      Affiliations

    • Co–authors of this article wish to remain anonymous. Nonetheless, their significant contributions to all phases of the work summarised in this paper, as well as in the preparation of this article, are recognised.

References 

  1. Henshaw SK, Singh S, Haas T. The incidence of abortion worldwide. International Family Planning Perspectives. 1999;25(Suppl.):S30–S38
  2. Åhman E, Shah I. Unsafe Abortion: Global and Regional Estimates of Incidence of Unsafe Abortion and Associated Mortality in 2000. 4th ed. Geneva: World Health Organization; 2004;
  3. Costa SH, Vessy MP. Misoprostol and illegal abortion in Rio de Janeiro, Brazil. Lancet. 1993;341:1258–1261
  4. Ashok PW, Penney GC, Flett GMM, et al. An effective regimen for early medical abortion: a report of 2000 consecutive cases. Human Reproduction. 1998;13(10):2962–2965
  5. Schaff EA, Fielding SL, Westhoff C, et al. Vaginal misoprostol administered 1, 2, or 3 days after mifepristone for early medical abortion: a randomized trial. JAMA. 2000;284:1948–1953
  6. In:  Abuabara K,  Blum J editor. Providing medical abortion in developing countries: an introductory guidebook. Results of a team residency at the Bellagio Study and Conference Center. New York: Gynuity Health Projects; 2004;
  7. See 〈http://www.medicationabortion.org/sidebars/misoprostolstudies.html〉, 〈http://www.ipas.org/english/publications/abortion.asp〉 and 〈http://www.medicationabortion.org/methotrexate/index.html〉. Accessed 9 December 2004.
  8. Bugalho A, Faúndes A, Jamisse L, et al. Evaluation of the effectiveness of vaginal misoprostol to induce first trimester abortion. Contraception. 1996;53(4):243–246
  9. Carbonell JL, Varela L, Velazco A, et al. The use of misoprostol for termination of early pregnancy. Contraception. 1997;55:165–168
  10. Carbonell JL, Varela L, Velazco A, et al. The use of misoprostol for abortion at less than or equal to 9 weeks' gestation. European Journal of Contraception and Reproductive Health Care. 1997;2(3):181–185
  11. Carbonell JL, Varela L, Velazco A, et al. Vaginal misoprostol for late first trimester abortion. Contraception. 1998;57(5):329–333
  12. Carbonell JL, Varela L, Velazco A, et al. Vaginal misoprostol for abortion at 10–13 weeks' gestation. European Journal of Contraception and Reproductive Health Care. 1999;4(1):35–40
  13. Carbonell JL, Rodriguez J, Aragon S, et al. Vaginal misoprostol 1000 micrograms for early abortion. Contraception. 2001;63(3):131–136
  14. Creinin MD, Vittinghoff E. Methotrexate and misoprostol vs. misoprostol alone for early aborton: a randomized controlled trial. JAMA. 1994;272:1190–1195
  15. Jain JK, Meckstroth KR, Michell DR. Early pregnancy termination with intravaginally administered sodium chloride solution-moistened misoprostol tablets: historical comparison with mifepristone and oral misoprostol. American Journal of Obstetrics and Gynecology. 1999;181(6):1386–1391
  16. Velazco A, Varela L, Tanda R, et al. Misoprostol for abortion up to 9 weeks' gestation in adolescents. European Journal of Contraception and Reproductive Health Care. 2000;5(4):227–233
  17. Blanchard K, Winikoff B, Coyaji K, et al. Misoprostol alone: a new method of medical abortion?. JAMWA. 2000;55(3 Suppl.):189–190
  18. Blanchard K, Winikoff B, Ellertson C. Misoprostol used alone for the termination of early pregnancy: a review of the evidence. Contraception. 1999;59(4):209–217
  19. World Health Organization. Safe Abortion: Technical and Policy Guidance for Health Systems. Geneva: WHO; 2003;
  20. Consensus Statement: Instructions for Use – Abortion Induction with Misoprostol in Pregnancies up to 9 Weeks LMP. Expert Meeting on Misoprostol sponsored by Reproductive Health Technologies Project and Gynuity Health Projects. Washington DC, 28 July 2003. At: 〈www.gynuity.org〉. Accessed 30 August 2004.
  21. Jain JK, Harwood B, Meckstroth KR, et al. Early pregnancy termination with vaginal misoprostol combined with loperamide and acetaminophen prophylaxis. Contraception. 2001;63(4):217–221
  22. Jain JK, Dutton C, Harwood B, et al. A prospective randomized, double-blinded, placebo-controlled trial comparing mifepristone and vaginal misoprostol to vaginal misoprostol alone for elective termination of pregnancy. Human Reproduction. 2002;17(6):1477–1482

PII: S0968-8080(04)24010-1

doi: 10.1016/S0968-8080(04)24010-1

Reproductive Health Matters
Volume 12, Issue 24, Supplement , Pages 57-64 , November 2004

Article Tools

* Image Usage & Resolution