Reproductive Health Matters
Volume 15, Issue 29 , Pages 33-44 , May 2007

Roundtable: Male Circumcision and HIV Prevention: Is There Really Enough of the Right Kind of Evidence?

  • Gary W Dowsett

      Affiliations

    • Professor and Deputy Director, Australian Research Centre in Sex, Health and Society, Faculty of Health Sciences, La Trobe University, Melbourne, Australia
    • ,
  • Murray Couch

      Affiliations

    • Senior Research Fellow, Australian Research Centre in Sex, Health and Society, La Trobe University, Melbourne

References 

  1. UNAIDS. Report on the Global AIDS Epidemic. Geneva: UNAIDS; 2006;
  2. Waldby C. AIDS and the Body Politic: Biomedical and Sexual Difference. London & New York: Routledge; 1996;
  3. Drain PK, Halperin DT, Hughes JP, et al. Male circumcision, religion, and infectious disease: an ecologic analysis of 118 developing countries. BMC Infectious Diseases. 2006;6:172
  4. Halperin DT, Bailey RC. Male circumcision and HIV infection: 10 years and counting. Lancet. 1999;354(9192):1813–1815
  5. Moses S, Bradley JE, Nagelkerke NJ, et al. Geographical patterns of male circumcision practices in Africa: association with HIV seroprevalence. International Journal of Epidemiology. 1990;19(3):693–697
  6. Moses S, Plummer FA, Bradley JE, et al. The association between lack of male circumcision and risk for HIV infection: a review of the epidemiological data. Sexually Transmissible Diseases. 1994;21(4):201–210
  7. Weiss HA, Quigley MA, Hayes RJ. Male circumcision and risk of HIV infection in sub-Saharan Africa: a systematic review and meta-analysis. AIDS. 2000;14(15):2361–2370
  8. Weiss HA, Thomas SL, Munabi SK, et al. Male circumcision and risk of syphilis, chancroid, and genital herpes: a systematic review and meta-analysis. Sexually Transmitted Infections. 2006;82(2):101–109
  9. Auvert B, Taljaard D, Lagarde E, et al. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 trial - art. no. e298. Plos Medicine 2005a;2(11):1112–22.
  10. Sayer A. In: Realism and Social Science. London: Sage; 2006;p. 14
  11. Pawson R. Evidence-Based Policy: A Realist Perspective. London: Sage; 2006;
  12. Gray RH, Kigozi G, Serwadda D, et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet. 2007;369(9562):657–666
  13. Bailey RC, Moses S, Parker CB, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet. 2007;369(9562):643–656
  14. McNeil DG. Circumcision's anti-AIDS effect found greater than first thought. New York Times. 23 February 2007;
  15. UNAIDS. Male Circumcision. 2006;At: < www.unaids.org/en/Policies/HIV_Prevention/Male_circumcision.asp>
  16. UNAIDS. Moving Forwards: UN Policy and Action on Male Circumcision (Part 3). 20 March 2007;At: < www.unaids.org/en/MediaCentre/PressMaterials/FeatureStory/20070302_MC_Pt3.asp>
  17. Ahmed A, Mbibi NH, Dawam D, et al. Complications of traditional male circumcision. Annals of Tropical Paediatrics. 1999;19(1):113–117
  18. Atikeler MK, Onur R, Gecit I, et al. Increased morbidity after circumcision from a hidden complication. BJU International. 2001;88(9):938–940
  19. Cathcart P, Nuttall M, van der Meulen J, et al. Trends in paediatric circumcision and its complications in England between 1997 and 2003. British Journal of Surgery. 2006;93(7):885–890
  20. Yegane RA, Kheirollahi AR, Salehi NA, et al. Late complications of circumcision in Iran. Pediatric Surgery International. 2006;22(5):442–445
  21. Kim D-S, Pang M-G. The effect of male circumcision on sexuality. BJU International. 2007;99(3):619–622
  22. Sorrells ML, Snyder JL, Reiss MD, et al. Fine-touch pressure thresholds in the adult penis. BJU International. 2007;99(4):864–869
  23. Rennie S, Westreich, Muula A. Male circumcision and HIV prevention: ethical, medical and public health trade-offs in low income countries. Journal of Medical Ethics, in press. Available online at: <http://jme.bmj.com/preprint/rennie.pdf>
  24. McCoombe SG, Short RV. Potential HIV-1 target cells in the human penis. AIDS. 2006;20:1491–1495p.1491
  25. Donoval BA, Landay AL, Moses S, et al. HIV-1 target cells in foreskins of African men with varying histories of sexually transmitted infections. American Journal of Clinical Pathology. 2006;125:386–391
  26. de Witt L, Nabatov A, Pion M, et al. Langerin is a natural barrier to HIV-1 transmission by Langerhans cells. Nature Medicine: Advance Online Publication 4 March 2007.
  27. Mishra V, Hong R, Khan S. Risk behaviors and patterns of HIV seroprevalence in countries with generalised epidemics: results from the demographic and health surveys. Published abstract at XVI International AIDS Conference Toronto, Canada, 13–18 August 2006.
  28. Way A, Mishra V, Hong KJ. Is male circumcision protective of HIV infection? Poster exhibition at XVI International AIDS Conference Toronto, Canada, 13–18 August 2006.
  29. Williams BG, Lloyd-Smith JO, Gouws E, et al. The potential impact of male circumcision on HIV in sub-Saharan Africa - art. no. e262. Plos Medicine. 2006;3(7):1032–1040
  30. Kippax S. Sexual health interventions are unsuitable for experimental evaluation. In:  Stephenson JM,  Imrie J,  Bonell C editor. Effective Sexual Health Education Interventions: Issues in Experimental Evaluation. Oxford: Oxford University Press; 2003;p. 17–34
  31. Brannigan A, Zwerman W. The real ‘Hawthorne Effect’. Society. 2001;38(2):55–60
  32. Moss LB. The Jewish roots of anti-circumcision arguments. Paper presented at Second International Symposium on Circumcision, San Francisco. 30 April–3 May 1991.
  33. Rothenberg M. Ending circumcision in the Jewish community. Paper presented at Second International Symposium on Circumcision, San Francisco. 30 April–3 May 1991.
  34. Kahn JG, Marseille E, Auvert B. Cost-effectiveness of male circumcision for HIV prevention in a South African setting. PLoS Medicine. 2006;3(12):2349–2358
  35. Agot KE, Kiarie JN, Nguyen HQ, et al. Male circumcision in Siaya and Bondo districts, Kenya: prospective cohort study to assess behavioural disinhibition following circumcision. Journal of Acquired Immune Deficiency Syndrome. 2006;44(1):66–70
  36. Muula AS, Prozesky HW, Mataya RH, et al. Prevalence of complications of male circumcision in Anglophone Africa: a systematic review. BMC Urology. 2007;7:4;doi:10.1186/1471-2490-7-4
  37. Sawires SR, Dworkin SL, Fiamma A, et al. Male circumcision and HIV/AIDS: challenges and opportunities. Lancet. 2007;369(9562):708–713
  38. NYC eyes circumcision push to fight AIDS. New York Times. 5 April 2007.
  39. Wilson D, de Beyer J. Male circumcision: evidence and implications. HIV/AIDS Monitoring & Evaluation – Getting Results. Washington DC: World Bank Report; 2006;
  40. UNAIDS. Male Circumcision: Global Trends and Determinants of Prevalence, Safety and Acceptability. Geneva: UNAIDS, in press.
  41. Zulu K, Bulawo ND, Zulu W. Circumcision razor a preventative tool or a strategic vector in the transmission of HIV? – a case of Zambia. Poster exhibition at XVI International AIDS Conference Toronto, Canada, 13–18 August 2006.
  42. Brewer DD, Potterat JJ, Roberts JM, et al. Male and female circumcision associated with prevalent HIV infection in virgins and adolescents in Kenya, Lesotho, and Tanzania. Annals of Epidemiology. 2007;17:217–266
  43. Hunter M. The changing political economy of sex in South Africa: the significance of unemployment and inequalities to the scale of the AIDS pandemic. Social Science & Medicine. 2007;64(3):689–700
  44. Bailey RC, Egesah O. Assessment of Clinical and Traditional Male Circumcision Services in Bungoma District, Kenya; Complications Rates and Operational Needs. A Special Report for USAID/PSI-AIDSMark, April 2006.
  45. Lake P, Hakim W. Using culture to fight culture: preventing HIV transmission by changing harmful practices surrounding circumcision of young men in East Nusa Tenggara, Indonesia. Oral presentation at XVI International AIDS Conference Toronto, Canada, 13–18 August 2006.
  46. Westercamp N, Bailey RC. Acceptability of male circumcision for prevention of HIV/AIDS in sub-Saharan Africa: a review. AIDS & Behavior 2006; (online journal) DOI: 10.1007/s10461-006-9169-4.
  47. World Health Organization. Demand for male circumcision rises in a bid to prevent HIV. Bulletin of World Health Organization. 2006;84(7):509–511
  48. Dowsett GW, Aggleton P, Abega S-C, et al. Changing gender relations among young people: the global challenge for HIV/AIDS prevention. Critical Public Health. 1998;8(4):291–309
  49. In:  Ross DA,  Dick B,  Ferguson J editor. Preventing HIV/AIDS in Young People: A Systematic Review of the Evidence from Developing Countries. World Health Organization Technical Report Series No 938. Geneva: WHO; 2006;
  50. Auvert B, Puren A, Taljaard D, et al. The impact of male circumcision on the female-to-male transmission of HIV: results of the intervention trial: ANRS 1265. Presentation to the International AIDS Society Conference, Rio de Janeiro, 27 July 2005. Slide 3.
  51. Ngalande RC, Levy J, Kapondo CPN, et al. Acceptability of male circumcision for prevention of HIV infection in Malawi. AIDS & Behavior. 2006;10(4):377–385

PII: S0968-8080(07)29302-4

doi: 10.1016/S0968-8080(07)29302-4

Reproductive Health Matters
Volume 15, Issue 29 , Pages 33-44 , May 2007

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